Fugitive Terry Hines, suspected of involvement with terrorists, has been on FBI Agent Tyler Bannister's radar for some time when Federal prosecutor Kendall Briggs is murdered and a microbiologist at the CDC is stabbed to death and a biotoxin is missing. Bannister suspects the crimes are all related. The investigation takes a personal turn when Bannister's daughter is kidnapped and he is in a race against time to save his daughter and neutralize a biological attack.